Ask your healthcare provider if you are not sure if your medicine is one of these medicines that affect the way certain liver enzymes work.Using KEVZARA with these medicines may increase your risk of infection It is especially important to tell your healthcare provider if you use take any prescription or nonprescription medicines, vitamins, or herbal supplements.It is not known if KEVZARA passes into your breast milk Talk to your healthcare provider about the best way to feed your baby if you use KEVZARA. are breastfeeding or plan to breastfeed.It is not known if KEVZARA will harm your unborn baby are pregnant or plan to become pregnant.plan to have surgery or a medical procedure.People who take KEVZARA should not receive live vaccines recently received or are scheduled to receive a vaccine.have had stomach (abdominal) pain or a condition known as diverticulitis (inflammation in parts of the large intestine) or ulcers in your stomach or intestines.Do not use KEVZARA if you are allergic to sarilumab or any of the ingredients of KEVZARA.īefore using KEVZARA, tell your healthcare provider if you.Get medical attention right away if you have any of the following signs: shortness of breath or trouble breathing feeling dizzy or faint swelling of your lips, tongue, or face moderate or severe stomach (abdominal) pain or vomiting or chest pain. SERIOUS ALLERGIC REACTIONS: Serious allergic reactions can happen with KEVZARA.Tell your healthcare provider if you have ever had any type of cancer. CANCER: KEVZARA may increase your risk of certain cancers by changing the way your immune system works.Call your healthcare provider right away if you have fever and stomach (abdominal) pain that does not go away. This happens most often in people who also take nonsteroidal anti-inflammatory drugs (NSAIDS), corticosteroids, or methotrexate. Some people using KEVZARA had tears in their stomach or intestine. TEARS (PERFORATION) OF THE STOMACH OR INTESTINES: Tell your healthcare provider if you have had a condition known as diverticulitis (inflammation in parts of the large intestine) or ulcers in your stomach or intestines.Your healthcare provider should do blood tests 4 to 8 weeks after starting KEVZARA and then every 6 months during treatment to check for an increase in blood cholesterol levels. You may also have changes in other laboratory tests, such as your blood cholesterol levels. Changes in test results are common with KEVZARA and can be severe. CHANGES IN CERTAIN LABORATORY TEST RESULTS: Your healthcare provider should do blood tests before and after starting KEVZARA to check for low neutrophil (white blood cells that help the body fight off bacterial infections) counts, low platelet (blood cells that help with blood clotting and stop bleeding) counts, and an increase in certain liver function tests.After starting KEVZARA, call your healthcare provider right away if you have any symptoms of an infection.live or have lived, or have traveled to certain parts of the country (such as the Ohio and Mississippi River valleys and the Southwest) where there is an increased chance of getting certain fungal infections (histoplasmosis, coccidioidomycosis, or blastomycosis).have TB, or have been in close contact with someone with TB.have diabetes, HIV, or a weakened immune system.
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Symptoms may include sweats or chills, muscle aches, a cough, shortness of breath, blood in your phlegm, weight loss, warm, red, or painful skin or sores on your body, diarrhea or stomach pain, burning when you urinate or urinating more often than normal, if you feel very tired, or if you are being treated for an infection, get a lot of infections or have repeated infections think you have an infection or have symptoms of an infection, with or without a fever.Your healthcare provider should monitor you closely for signs and symptoms of TB during treatment with KEVZARA.īefore starting KEVZARA, tell your healthcare provider if you Your healthcare provider should test you for TB before starting KEVZARA. Some people have died from these infections. Some people have had serious infections while using KEVZARA, including tuberculosis (TB), and infections caused by bacteria, fungi, or viruses that can spread throughout the body. KEVZARA can lower the ability of your immune system to fight infections. SERIOUS INFECTIONS: KEVZARA is a medicine that affects your immune system. Important Safety Information KEVZARA® (sarilumab) can cause serious side effects including:
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